With Kimber Kable, the answer is no! There will be no audible difference in sound provided the shorter cable is greater than half the length of the longer one. Its a great way to save money and keep your room tidy.
Here is an example: Right Channel = 3.6m Left Channel 2.2m is OK, but 1.0m + 4.0m is not recommended (here we would suggest increasing the 1.0m to 2.0m).